Purpose: Radiation cystitis (RC), a severe inflammatory bladder condition, develops as a side effect of pelvic radiation therapy in cancer patients.There are currently no effective therapies to treat RC, in part from the lack of preclinical model systems.In this study, we developed a mouse model for RC and used a Small Animal Radiation Research Pla
Taking the welded rotor of Headbands steam turbine as the research object, a two-dimensional axisymmetric finite element model of multi-layer and multi-pass TIG are welding process was established.By using the double ellipsoidal heat source model, the element birth and death method and the Dflux heat source movement subroutine, the welding process
Abstract Background Metagenomics is the study of the microbial genomes isolated from communities found on our bodies or in our environment.By correctly determining the relation between human health and the human associated microbial communities, novel mechanisms of health and disease can be found, thus enabling the development of novel diagnostics
The complex life cycle of oncogenic human papillomavirus (HPV) initiates in undifferentiated basal epithelial keratinocytes where expression of the E6 and E7 oncogenes is restricted.Upon epithelial differentiation, E6/E7 transcription is increased through unknown mechanisms to drive cellular proliferation required to support virus replication.We re